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- FUNCTION-
-
- Folacin is important in the
- synthesis of DNA. It helps
- convert vitamin B12 to a co-
- enzyme to produce red blood
- cells. It controls cell function
- and tissue growth. Because
- it helps to control cell growth
- and function, some studies
- show it may lower the risk of
- birth defects such as spina
- bifida. Recent studies show
- it may be helpful in prevent-
- ing cervical cancer, and with
- vitamins B6 and B12 may
- help lower blood levels of
- homocysteine, an amino acid
- associated with increased
- risk of heart disease.
-
-
- FOOD SOURCES-
-
- Dark green leafy vegetables,
- citrus fruits and juices, beans
- and other legumes, wheat
- bran and other whole grains,
- pork, poultry, shellfish, liver
- and other organ meats.
-
-
- RISKS WITH EXCESS-
-
- Folacin is relatively nontoxic,
- except at doses more than
- 100 times the RDA (Recom-
- mended Dietary Allowance).
- Levels above 1 mg per day
- (5 times the RDA) may mask
- symptoms of vitamin B12 de-
- ficiency and pernicious ane-
- mia.
-
-
- RISKS WITH DEFICIENCY-
-
- Some people who might be
- deficient in folacin are alco-
- holics or people whose diets
- lack fresh, uncooked, or
- lightly cooked fruits and
- vegetables. People who are
- deficient in vitamins B12 or C
- might be deficient in folacin.
- Pregnant women and infants
- are most likely to be deficient.
- Some people might not ab-
- sorb the nutrient well due to
- liver disease, drug inter-
- actions, or disorders of the
- small intestine.
-
-
-